Were characterized for their structure and physico-chemical and mechanical properties, highlighting PBCA was synthetized, and then electrospun to produce aligned nanofibers. These wereĭeveloped as implants to be sutured to reconstruct the tendons and the ligaments during surgery. Mimic the hierarchical structure of the tendon and to improve the tissue healing potential. Synthetic polymer, doped with copper oxide nanoparticles and caseinphosphopeptides (CPP), able to Scaffolds based on poly(butyl cyanoacrylate) (PBCA), a well-known biodegradable and biocompatible The aim of the present work was the design of nano-fibrous To overcome these limitations, innovative strategies for the treatment Treatment, and they largely fail due to the tissues weakening and the postoperative alterations of Traditional approaches require long periods of Pain, healthcare costs, and a loss of productivity. Tendon disorders are common medical conditions that could lead to significant disability, and Darioīozzo for the SEM analysis of the bacteria. The University of Pavia and Alessandro Girella for the SEM analysis, and Alfatest S.r.l. Pavia, Teresa Recca and Massimo Boiocchi for the NMR and TEM analysis, Centro Interdipartimentaleĭi Studi e Ricerche per la Conservazione del Patrimonio Culturale (CISRiC)-Arvedi Laboratory of The authors also acknowledge Centro Grandi Strumenti of the University of Support for X-ray experiments (doi:10.15151/ESRF-ES-585935736) and ID02 staff for their precious Supplementary Materials: The following supporting information can be downloaded at: es_ESĪcknowledgments: The authors acknowledge ESRF (Grenoble, Fr) for beamtime allocation and financial Electrospun Scaffolds Based on Poly(butyl cyanoacrylate) for Tendon Tissue Engineering.
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